Antibiotics: DNA, folate and tuberculosis
Fluoroquinolones, folate antagonists, metronidazole, nitrofurantoin and the first-line drugs for tuberculosis. 11 drugs in 5 classes. Read them through, then practice: their classes, how they work, what they treat and what they're known for. 13 questions, about 4 minutes.
Free, and no account needed.
In this group
The classes and their drugs
- FluoroquinolonesBlocking DNA gyrase and topoisomerase IV, so bacteria cannot copy their DNA
- CiprofloxacinLevofloxacinMoxifloxacin
- Antibacterial folate antagonistsBlocking the pathway bacteria use to make folate, needed for nucleic acids
- SulfamethoxazoleTrimethoprim
- NitroimidazolesForming DNA-damaging radicals once reduced inside anaerobic microbes
- Metronidazole
- NitrofuransForming reactive products inside bacteria that damage their DNA and proteins
- Nitrofurantoin
- First-line tuberculosis drugsAttacking TB bacteria at several targets at once, always given together
- IsoniazidRifampicinPyrazinamideEthambutol