Antibiotics: protein synthesis
Macrolides, tetracyclines, aminoglycosides and others that stop the bacterial ribosome making proteins. 10 drugs in 6 classes. Read them through, then practice: their classes, how they work, what they treat and what they're known for. 14 questions, about 5 minutes.
Free, and no account needed.
In this group
The classes and their drugs
- MacrolidesBinding the 50S ribosomal subunit so the growing protein chain cannot move on
- AzithromycinClarithromycinErythromycin
- TetracyclinesBinding the 30S ribosomal subunit so tRNA cannot bring in new amino acids
- DoxycyclineTetracycline
- AminoglycosidesBinding the 30S subunit so mRNA is misread and faulty proteins are made
- GentamicinAmikacin
- LincosamidesBinding the 50S subunit so unfinished peptide chains drop off the ribosome
- Clindamycin
- OxazolidinonesBlocking formation of the 70S initiation complex on the 50S subunit
- Linezolid
- AmphenicolsBlocking peptidyl transferase on the 50S subunit so no peptide bonds form
- Chloramphenicol