Cancer chemotherapy
Alkylating agents, platinum drugs, antimetabolites, anthracyclines and the drugs that act on microtubules. 9 drugs in 7 classes. Read them through, then practice: their classes, how they work, what they treat and what they're known for. 15 questions, about 5 minutes.
Free, and no account needed.
In this group
The classes and their drugs
- Alkylating agentsCross-linking DNA strands with alkyl groups so cells cannot divide
- Cyclophosphamide
- Platinum compoundsBinding DNA through platinum to form cross-links that block replication
- CisplatinCarboplatin
- AntimetabolitesMimicking DNA building blocks or their cofactors to block DNA synthesis
- MethotrexateFluorouracil
- AnthracyclinesIntercalating into DNA and trapping topoisomerase II so DNA breaks stay open
- Doxorubicin
- Vinca alkaloidsBlocking tubulin assembly into microtubules so the mitotic spindle fails
- Vincristine
- TaxanesStabilizing microtubules so they cannot break down and mitosis stalls
- Paclitaxel
- Topoisomerase II inhibitorsBlocking topoisomerase II from resealing DNA, leaving double-strand breaks
- Etoposide