Blood clots and cholesterol
Anticoagulants, antiplatelets, clot busters, tranexamic acid, and the drugs that lower cholesterol. 19 drugs in 10 classes. Read them through, then practice: their classes, how they work, what they treat and what they're known for. 16 questions, about 5 minutes.
Free, and no account needed.
In this group
The classes and their drugs
- HeparinsBoosting antithrombin, which then switches off thrombin and factor Xa
- HeparinEnoxaparin
- Vitamin K antagonistsBlocking vitamin K recycling, so the liver makes inactive clotting factors
- Warfarin
- Direct factor Xa inhibitorsBinding factor Xa directly, so less thrombin is made
- RivaroxabanApixabanEdoxaban
- Direct thrombin inhibitorsBinding thrombin directly, so fibrinogen is not turned into fibrin
- Dabigatran
- P2Y12 inhibitorsBlocking the platelet ADP receptor P2Y12, so platelets clump less
- ClopidogrelTicagrelorPrasugrel
- ThrombolyticsTurning plasminogen into plasmin, which breaks down the fibrin in clots
- AlteplaseTenecteplase
- AntifibrinolyticsBlocking plasminogen's lysine sites, so clots are not broken down
- Tranexamic acid
- StatinsBlocking HMG-CoA reductase, so the liver makes less cholesterol
- AtorvastatinSimvastatinRosuvastatinPravastatin
- Cholesterol absorption inhibitorsBlocking the gut cholesterol transporter NPC1L1, so less cholesterol is absorbed
- Ezetimibe
- FibratesActivating PPAR-alpha, so triglyceride-rich particles are cleared faster
- Fenofibrate