Heart failure, rhythm and angina
Drugs for a failing heart, an irregular rhythm and chest pain: loop diuretics, aldosterone blockers, nitrates, digoxin and amiodarone. 10 drugs in 6 classes. Read them through, then practice: their classes, how they work, what they treat and what they're known for. 14 questions, about 5 minutes.
Free, and no account needed.
In this group
The classes and their drugs
- Loop diureticsBlocking NKCC2 in the loop of Henle, so much more salt and water is lost
- FurosemideBumetanideTorasemide
- Mineralocorticoid receptor antagonistsBlocking aldosterone receptors, so sodium is lost and potassium kept
- SpironolactoneEplerenone
- Angiotensin receptor-neprilysin inhibitorsInhibiting neprilysin to boost natriuretic peptides, with AT1 receptor block
- Sacubitril/valsartan
- NitratesReleasing nitric oxide, so veins and arteries relax and preload falls
- Glyceryl trinitrateIsosorbide mononitrate
- Cardiac glycosidesInhibiting the sodium pump, so heart cells gain calcium and contract harder
- Digoxin
- Class III antiarrhythmicsBlocking cardiac potassium channels, so repolarization and the QT lengthen
- Amiodarone