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Life Science Dictionary

Hepatitis

Medicine · Virology · Pathology

Say it: hep-uh-TY-tis

Hepatitis is liver inflammation, most often caused by a hepatitis virus but also by alcohol, toxins, some medicines or autoimmune disease.

Definition

What is hepatitis?

In hepatitis the liver, the organ that filters the blood, processes drugs and alcohol and makes bile, becomes inflamed. The illness can be acute, lasting weeks, or chronic, lasting six months or more. Five unrelated viruses, named hepatitis A to E, are the best-known causes, but heavy drinking, some medicines and toxins, and autoimmune hepatitis, in which the immune system attacks liver cells, can also inflame the organ.

Hepatitis A and E pass mainly through food or water contaminated with feces and usually clear up on their own. Hepatitis B, C and D spread through blood, and B and D also through other body fluids, including from mother to baby at birth; these can last for decades, and D can only infect someone who already carries B. Many infected people feel well, while others have tiredness, nausea, dark urine and jaundice, a yellowing of the skin and eyes. Years of chronic B or C infection can scar the liver into cirrhosis and lead to liver cancer.

Blood tests for liver enzymes and for viral antigens, antibodies or genetic material identify the type. Vaccines prevent hepatitis A and B, chronic B is kept in check with antiviral drugs, and most hepatitis C infections can now be cured with a short course of pills.

Word parts

Where does the word “hepatitis” come from?

hepat-
liverGreek hepar, hepatos
-itis
inflammationGreek -itis

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