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Parasympathetic nervous system

Neuroscience · Physiology

Say it: pair-uh-sim-puh-THET-ik NUR-vus SIS-tum

The parasympathetic nervous system is the autonomic division that conserves energy and controls rest-and-digest activities such as digestion.

Also: parasympathetic division, craniosacral division

Definition

What is the parasympathetic nervous system?

The parasympathetic nervous system is the second main division of the autonomic nervous system. Its first neurons sit in nuclei of the brainstem and in the sacral part of the spinal cord, so it is also called the craniosacral division. Their axons leave through four cranial nerves, the oculomotor, facial, glossopharyngeal and vagus nerves, and through sacral spinal nerves. Unlike sympathetic fibers, these preganglionic axons are long and end in terminal ganglia lying next to, or inside the wall of, the organ they control, so the second neurons are short.

Parasympathetic activity slows the heart, narrows the pupils and airways, increases the flow of saliva and tears, stimulates gut movement and digestive secretions, and helps empty the bladder. The vagus nerve carries most of this output to the heart, lungs and abdominal organs. Both the preganglionic and the postganglionic neurons release acetylcholine, which acts on nicotinic receptors in the ganglia and mainly on muscarinic receptors in the target tissues.

Most organs receive both divisions, and their opposing effects keep functions such as heart rate in balance. Drugs that block muscarinic receptors, such as atropine, speed the heart and dry the mouth, while drugs that mimic acetylcholine are used for some eye and bladder conditions.

Word parts

Where does the term “parasympathetic nervous system” come from?

para-
beside, alongsideGreek para
sym-
together, withGreek syn
-pathetic
feelingGreek pathos, via sympatheia

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