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Life Science Dictionary

Risk factor

Epidemiology · Public Health

Say it: RISK FAK-tur

A risk factor is a trait, exposure or behavior linked to a higher chance of developing a particular disease, injury or other health problem.

Also: risk factors

Definition

What is a risk factor?

A risk factor is any characteristic, habit or exposure associated with an increased likelihood of a disease, injury or death. Risk factors are identified through epidemiological studies that compare how often an outcome occurs in people with and without the factor, and the strength of the link is usually expressed as a relative risk or odds ratio. Some risk factors are causes in their own right, while others are markers that travel with a cause.

They are often divided into fixed factors, such as age, sex, family history and inherited gene variants, and modifiable ones that people or policies can change. The World Health Organization highlights tobacco use, physical inactivity, unhealthy diets, harmful drinking of alcohol and air pollution as major modifiable risk factors for noncommunicable diseases, along with metabolic risk factors such as raised blood pressure, high blood glucose, high blood lipids and obesity. Some infections, radiation and workplace chemicals are risk factors for particular cancers.

Having a risk factor does not mean a person will develop the disease, and many people become ill without any known risk factor. The opposite is a protective factor, such as vaccination, which lowers the chance. Finding modifiable risk factors is the basis of prevention programs and of screening aimed at higher-risk groups.

Word parts

Where does the term “risk factor” come from?

risk
danger, hazardFrench risque, from Italian risco
fact-
to make, do (factor: a maker, doer)Latin facere

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