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Life Science Dictionary

Obesity

Medicine · Food Nutrition · Public Health

Say it: oh-BEE-sih-tee

Obesity is a chronic disease in which excess body fat builds up enough to harm health, defined in adults as a body mass index of 30 or more.

Definition

What is obesity?

Obesity is an excess of body fat large enough to raise the risk of illness and early death. In adults it is usually screened for with body mass index (BMI), which compares weight with the square of height, in kilograms per square meter: 25 or more counts as overweight and 30 or more as obesity. Because BMI does not show where fat is stored, waist circumference is often measured too, since fat around the abdominal organs carries the greatest risk. Children are assessed against growth references for their age and sex.

At its simplest, obesity results from taking in more energy than the body uses over a long period, but many factors shape that balance: genes, which strongly influence body weight; hormones such as leptin that signal fullness to the hypothalamus; sleep, stress and some medicines; and surroundings full of cheap, energy-dense food with little need for physical activity. It is a major risk factor for type 2 diabetes, heart disease, stroke, fatty liver disease, sleep apnea, osteoarthritis and several cancers.

More than a billion people live with obesity worldwide, and rates have risen sharply since 1990. Treatment combines changes in diet and activity with, for many people, medicines such as GLP-1 receptor agonists or weight-loss (bariatric) surgery.

Word parts

Where does the word “obesity” come from?

obes-
fat, stout; literally having eaten oneself fatLatin obesus, from ob-, over + edere, to eat

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