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Life Science Dictionary

Fatty acid

Biochemistry · Food Nutrition

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A fatty acid is a long chain of carbon and hydrogen atoms with a carboxyl group at one end, and is the building block of fats, oils and phospholipids.

Also: fatty acids

Definition

What is a fatty acid?

A fatty acid is a hydrocarbon chain, a backbone of carbon atoms carrying hydrogen atoms, that ends in a carboxyl group (COOH), the acidic part that gives the molecule its name. Chains in living things range from about 4 to 36 carbons, and most have 12 to 18. Three fatty acids attached to glycerol make a triglyceride, the main form of stored fat, and two attached to a glycerol phosphate make a phospholipid.

Fatty acids are classed by their bonds. Saturated fatty acids have only single bonds between carbons, so their straight chains pack tightly, and fats rich in them, such as butter, are solid at room temperature. Unsaturated fatty acids have one double bond (monounsaturated) or more (polyunsaturated); a cis double bond puts a kink in the chain, which keeps oils liquid. Partly hydrogenating oils can create trans fatty acids, which are linked to raised LDL cholesterol.

The body cannot make omega-3 and omega-6 fatty acids, so they are essential in the diet; oily fish, walnuts and flaxseed are rich sources of omega-3s. When energy is needed, cells break fatty acids down by beta-oxidation, feeding the citric acid cycle.

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