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Life Science Dictionary

Lipid

Biochemistry · Cell Biology · Food Nutrition

Say it: LIP-id

A lipid is one of a varied group of biological molecules, including fats, oils, phospholipids, waxes and steroids, that do not dissolve in water.

Also: lipids

Definition

What is a lipid?

Lipids are a large and varied family of biological molecules grouped by a shared physical property rather than a shared structure. They are hydrophobic, meaning they do not mix with water, but they dissolve in nonpolar solvents such as ether or chloroform. This is because they are made mostly of carbon and hydrogen joined by nonpolar bonds. The main kinds students learn are fats and oils (triglycerides), phospholipids, steroids such as cholesterol, and waxes.

Lipids do several jobs. Triglycerides, built from glycerol and three fatty acids, store energy compactly and insulate the body. Phospholipids have a water-loving phosphate head and two water-avoiding fatty acid tails, so in water they line up into the double layer, or bilayer, that forms every cell membrane. Steroids serve as hormones, waxes waterproof leaves and feathers, and vitamins A, D, E and K are fat-soluble lipids that travel with dietary fat.

In medicine, the word turns up in the lipid panel, a routine blood test that measures cholesterol and triglycerides, which are carried through the blood in particles called lipoproteins.

Word parts

Where does the word “lipid” come from?

lip-
fatGreek lipos

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