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Life Science Dictionary

Flagellum

Microbiology · Cell Biology

Say it: fluh-JEL-um

A flagellum is a long, whip-like projection that some cells, including many bacteria and sperm, use to swim through liquid.

Also: flagella

Definition

What is a flagellum?

A flagellum is a thin, tail-like structure that sticks out from a cell and drives it through fluid. Bacteria, archaea and many eukaryotic cells have flagella, but the three kinds are built differently and evolved separately. In bacteria the flagellum has three parts: a basal body anchored in the cell envelope, which works as a rotary motor; a short curved hook that acts as a joint; and a long, stiff, helical filament made of many thousands of copies of the protein flagellin. Ions, usually protons, flowing into the cell through the motor's stator units turn the rotor, and the filament spins like a propeller.

Bacteria are described by how their flagella are arranged: a single one at a pole (monotrichous, as in Vibrio cholerae), a tuft at one end (lophotrichous), flagella at both ends (amphitrichous) or all over the surface (peritrichous, as in E. coli). During chemotaxis, counterclockwise rotation bundles the filaments so the cell swims straight in a run, while clockwise rotation splays them so the cell tumbles and changes direction.

A eukaryotic flagellum, such as a sperm tail, is instead a whip that bends, powered by dynein motors acting on a 9 + 2 ring of microtubules inside the cell membrane.

Word parts

Where does the word “flagellum” come from?

flagellum
little whipLatin, diminutive of flagrum (whip)

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