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Life Science Dictionary

Diploid

Genetics · Cell Biology

Say it: DIP-loyd

Diploid describes a cell or organism with two complete sets of chromosomes, one inherited from each parent, as in most human body cells.

Also: diploidy

Definition

What does diploid mean?

A diploid cell contains two full sets of chromosomes, written 2n. Each chromosome is present as a matched pair of homologs, which carry the same genes in the same order; one homolog came from the mother and one from the father, so the two may hold different alleles. Human body cells are diploid, with 46 chromosomes in 23 pairs: 22 pairs of autosomes and one pair of sex chromosomes.

Diploidy is kept in balance by the cycle of meiosis and fertilization. Meiosis halves the chromosome number to make haploid gametes, and the fusion of an egg and a sperm restores two sets in the zygote. Mitosis then passes the full diploid set to every new body cell. Having two copies of each gene allows a recessive allele to be masked by a dominant one, which is why a person can carry a recessive condition without showing it.

Most animals and many plants are diploid for most of their life cycle. Some organisms have more than two sets, a state called polyploidy that is common in crop plants: bread wheat has six sets of chromosomes, and cultivated strawberries have eight.

Word parts

Where does the word “diploid” come from?

diplo-
double, twofoldGreek diploos
-oid
like, having the form ofGreek eidos (form)

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