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Life Science Dictionary

Haploid

Genetics · Cell Biology

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Haploid describes a cell or organism that has a single set of chromosomes, such as a human egg or sperm cell with 23 chromosomes.

Also: haploidy

Definition

What does haploid mean?

A haploid cell carries one set of chromosomes, so each kind of chromosome is present only once. Geneticists write this number as n. In humans n is 23, and the only haploid cells are the gametes, eggs and sperm, which form by meiosis from diploid cells with 46 chromosomes (2n). When an egg and a sperm fuse at fertilization, the zygote regains two sets. Halving the number in meiosis and doubling it at fertilization keeps the chromosome count steady across generations.

Because a haploid cell has just one copy of each gene, any recessive allele it carries is expressed, with no second copy to hide it. This makes haploid organisms useful in genetics research. Baker's yeast, Saccharomyces cerevisiae, can grow as either haploid or diploid cells, so mutations are easy to detect in its haploid form.

Many organisms spend much of their lives haploid. Most fungi and many algae have a haploid body, and their zygote, the only diploid cell, quickly undergoes meiosis. Plants alternate between a haploid gametophyte and a diploid sporophyte. In bees, wasps and ants, males usually hatch from eggs that were never fertilized and so are haploid, whereas females are diploid.

Word parts

Where does the word “haploid” come from?

haplo-
single, simpleGreek haploos
-oid
like, having the form ofGreek eidos (form)

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