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Life Science Dictionary

pH

Biochemistry · Physiology

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pH is a number, usually on a scale of 0 to 14, that shows how acidic or basic a water-based solution is from its concentration of hydrogen ions.

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What is pH?

pH is a measure of how acidic or basic (alkaline) a solution in water is. Formally, it equals minus the base-10 log of the hydrogen ion concentration in moles per liter, written pH = -log[H+]; chemists often write the ion as hydronium, H3O+. Pure water at 25 °C contains equal amounts of hydrogen and hydroxide ions and has a pH of 7, which is neutral. Values below 7 are acidic and values above 7 are basic.

Because the scale is logarithmic, each step of one unit is a tenfold change in hydrogen ion concentration, so a solution at pH 3 is ten times more acidic than one at pH 4. Living things must keep pH within narrow limits, since it alters the charges and shapes of proteins and so the activity of enzymes. Human blood stays close to 7.4, held there by buffers such as the carbonic acid and bicarbonate system, while stomach acid sits at about 1 to 2.

In the lab, pH is measured with a pH meter or estimated with indicator paper. The symbol is usually read as 'power of hydrogen', though the origin of the p is debated.

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