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Life Science Dictionary

Kidney

Human Anatomy · Physiology

Say it: KID-nee

The kidneys are two bean-shaped organs that filter the blood to make urine, balancing the body's water, salts and acid and helping set blood pressure.

Also: kidneys

Definition

What are the kidneys?

The kidneys are a pair of bean-shaped organs, each roughly the size of a fist, that sit against the back wall of the abdomen on either side of the spine, just below the rib cage. Each has an outer cortex, an inner medulla arranged in cone-shaped pyramids, and a funnel called the renal pelvis that drains urine into the ureter.

The working units are microscopic nephrons, about a million in each kidney. In every nephron a tuft of capillaries, the glomerulus, filters water and small molecules out of the blood, and a long tubule then reclaims what the body needs and adds further wastes. Only a small fraction of the filtered fluid leaves as urine. At rest, the kidneys receive about a quarter of all the blood the heart pumps.

Besides removing urea and other wastes, the kidneys keep sodium, potassium, calcium and acid levels steady. They also act as endocrine organs: they help regulate blood pressure, release erythropoietin, the hormone that prompts the marrow to produce red blood cells, and activate vitamin D for healthy bones. Clinicians track how well the kidneys work with the glomerular filtration rate.

Word parts

Where does the word “kidney” come from?

nephr-
kidney; used in words such as nephron and nephrologyGreek nephros
ren-
kidney; the source of the adjective renalLatin renes (kidneys)

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