ATP
Say it: ay-tee-PEE
Short for adenosine triphosphate
ATP (adenosine triphosphate) is the molecule cells use as their main short-term energy carrier, releasing energy when a phosphate group is removed.
Also: adenosine triphosphate
Definition
What is ATP?
ATP is a nucleotide made of the base adenine, the five-carbon sugar ribose and a chain of three phosphate groups. It is often called the energy currency of the cell because it links reactions that release energy, such as the breakdown of glucose, to processes that need energy, such as muscle contraction, building large molecules and pumping ions across membranes.
The bonds between the phosphate groups break easily. When water splits off the outermost phosphate, ATP becomes ADP (adenosine diphosphate) plus inorganic phosphate, and energy is released. Cells put that energy to work by transferring the phosphate to another molecule, which changes its shape or makes it more reactive. ADP is then recharged into ATP, mostly by the enzyme ATP synthase in mitochondria during oxidative phosphorylation, with smaller amounts made directly in glycolysis and the citric acid cycle, and in chloroplasts during photosynthesis.
A cell keeps only a small stock of ATP and recycles it constantly. ATP is also one of the building blocks used to make RNA, and outside cells it acts as a signaling molecule, including as a neurotransmitter.
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Terms that go with it
- MitochondrionA mitochondrion is a double-membraned organelle that makes most of a eukaryotic cell's ATP by breaking down fuel molecules with oxygen.
- Oxidative phosphorylationOxidative phosphorylation is how cells make most of their ATP, using a proton gradient built by the electron transport chain to drive ATP synthase.
- GlycolysisGlycolysis is the ten-step metabolic pathway that splits one glucose molecule into two pyruvate molecules, giving a net gain of two ATP.
- NucleotideA nucleotide is a single unit of DNA or RNA, made of a nitrogen-containing base, a five-carbon sugar and one or more phosphate groups.
- MetabolismMetabolism is the full set of chemical reactions in a cell or organism, both those that break molecules down for energy and those that build them up.
- Active transportActive transport is the movement of a substance across a cell membrane against its concentration gradient, powered by energy, usually from ATP.
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