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Central nervous system

Neuroscience · Human Anatomy

Say it: SEN-trul NUR-vus SIS-tum

The central nervous system is the brain and spinal cord, the part of the nervous system that takes in sensory input, integrates it and sends out commands.

Also: CNS

Definition

What is the central nervous system?

The central nervous system, or CNS, comprises the brain and the spinal cord. It is the body's main processing center: it receives information from the senses, combines it with memory and emotion, and sends out commands to muscles and glands. Everything outside it, including the cranial and spinal nerves and their ganglia, belongs to the peripheral nervous system.

CNS tissue is divided into gray matter, rich in neuron cell bodies and dendrites, and white matter, made mostly of myelinated axons. Clusters of cell bodies inside the CNS are called nuclei, and bundles of axons are called tracts. Several kinds of glial cell work only here: oligodendrocytes make myelin, astrocytes support neurons and help form the blood-brain barrier, and microglia act as resident immune cells.

The brain sits in the skull and the spinal cord in the vertebral canal. Both are wrapped in three membranes, the meninges (dura mater, arachnoid mater and pia mater), and cushioned by cerebrospinal fluid. Strokes, infections, injuries, tumors and diseases such as multiple sclerosis can all damage the CNS.

Word parts

Where does the term “central nervous system” come from?

centr-
centerLatin centrum
nerv-
sinew, nerveLatin nervus

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